In the healthcare and pharmacy industry, protecting workers from hazardous drugs, such as chemotherapy agents, is a top priority. The United States Pharmacopeia (USP) Chapter 800 establishes stringent guidelines for ensuring safety through the use of personal protective equipment (PPE).
Understanding USP 800 Cleanroom Requirements
USP 800 aims to enhance safety measures in facilities handling hazardous drugs. It outlines specific requirements for PPE, which acts as a crucial barrier against contamination and exposure.
Key PPE Requirements:
- Gloves: Use ASTM-tested, powder-free, double-gloved protection to prevent exposure.
- Gowns: Wear single-use, disposable gowns made of polyethylene-coated polypropylene for maximum protection.
- Head, Hair, Shoe, and Sleeve Covers: Utilize waterproof, non-shedding covers to prevent contamination.
- Eye and Face Protection: Wear goggles and full-face respirators to shield against potential exposure.
- Respiratory Protection: Use NIOSH-certified N95 masks or activated-charcoal R95 masks for airborne particle and vapor protection.
The Role of PPE in Compounding Pharmacies
Compounding pharmacies must adhere to USP 800 guidelines to ensure employee and customer safety. This includes selecting appropriate cleanroom garments that meet stringent cleanliness and protection standards.
Choosing the Right Cleanroom Apparel
When selecting cleanroom garments, consider:
- Particle Cleanliness: Ensure garments meet specific particle cleanliness levels.
- Electrostatic Properties: Choose garments with anti-static properties to prevent particle attraction.
- Durability and Comfort: Select garments that are durable, comfortable, and allow for easy movement.
- Chemical Compatibility: Ensure garments are resistant to hazardous drug chemicals.
By adhering to USP 800 guidelines and selecting appropriate PPE, healthcare facilities can significantly reduce the risk of exposure to hazardous drugs and protect the health and safety of their workers.